Searchable abstracts of presentations at key conferences in endocrinology

ea0063gp87 | Thyroid Nodules and Cancer | ECE2019

Intronic RAS and PI3KCA mutations identified by Next Generation Sequencing in thyroid nodules with indeterminate cytology may associate with follicular thyroid cancer

Borges de Souza Patricia , Rossi Lucrezia , Crociara Anna , Rossi Roberta , Ambrosio Maria Rosaria , Rossi Martina , Bondanelli Marta , Lanza Giovanni , Zatelli Maria Chiara

Introduction: Accurately discern malignant from benign nodules sometimes represents a real challenge. Fine needle aspiration (FNA) biopsy, ultrasound and The Bethesda System for Reporting Thyroid Cytopathology (BSRTC) allow for accurate diagnosis in 60–80% of all nodules. However, 10–20% of thyroid FNAs yield an indeterminate cytology (BSRTC III and IV categories). The real malignancy rate of BSRTC III category is difficult to ascertain because histopathological anal...